Julianne Nicholson (LAW & ORDER: CRIMINAL INTENT) is said to be in talks to play his mother.
In the comics, it was revealed in later years that Peter’s parents Richard and Mary Parker were spies for the U.S. government (agents of S.H.I.E.L.D), and killed in the line of duty when he was quite young. One of the various Red Skulls was involved with their death, framing them as traitors.
Irrfan Khan (SLUMDOG MILLIONAIRE) and Annie Parisse (RUBICON) are reported to be under consideration to play a villainous couple, Khan’s character named Van Atter, with Parisse as his wife.
No details as yet about how much of a part any of these characters will play in the film.